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Prof. Dr. Ulrich Egert

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Prof. Dr. Ulrich Egert

Kandidat Sektionssprecher "Computational Neuroscience"

Department of Microsystems Engineering
Faculty of Engineering
Universität Freiburg
Institut für Mikrosystemtechnik – IMTEK
Professur für Biomikrotechnik
Georges-Köhler-Allee 102
79110 Freiburg
Email: egert@imtek.de
Tel.: +49 761 203-7524
Fax: +49 761 203-97759

Curriculum Vitae

Professional Experience

2008-present Professor for Biomicrotechnology (W3), Department of Microsystems Engineering, Faculty of Engineering and Director of the  Bernstein Center Neuroscience Freiburg, Univ. Freiburg, Germany
2005 Habilitation, Faculty of Biology, Dept. of Neuroscience and Biophysics, Univ. Freiburg, Germany
2001-2007 Assistant Professor (C1), Applied Neuroscience, Dept. of Neuroscience and Biophysics, Fac. of Biology, Univ. Freiburg, Germany
1996-2007 Head of the Applied Neuroscience Laboratory, Dept. of Neuroscience and Biophysics, Fac. of Biology, Univ. Freiburg, Germany
1988–1996 PhD-Student and Research Associate, Natural and Medical Sciences Institute (NMI) at the University of Tübingen, Reutlingen, Germany


Education and Training

1995 Dr. rer. nat.–  Univ. Tübingen, Germany, Thesis on the development of thin-film microelectrode arrays and their application in neurophysiology
1987 Diploma in Biology, Thesis on the effects of anesthetics on cortical visual plasticity and memory consolidation in kittens. Univ. Tübingen, Germany
1982-1983 Graduate studies in Zoology, Duke University, Durham, NC, USA (DAAD Fellowship)
1980-1987 Undergraduate and graduate studies in biology, Univ. Tübingen, Germany and Duke Univ., USA

 

Research Topics

  • Mechanisms and function of spatial and temporal activity dynamics in biological and computational neuronal networks under physiological and pathophysiological conditions
  • Activity-dependent homeostatic development of neuronal networks
  • Neurotechnological hybrid systems

 

Honors

  • Founding Member of the Board of the Bernstein Center Freiburg
  • Coordinator of the Bernstein Focus: Neurotechnology Freiburg/Tübingen – “Hybrid Brain”
  • Founding Member of the Board of the
  • Cluster of Excellence BrainLinks – BrainTools, Univ. Freiburg
  • Founding Member of the Board of the
  • Bernstein Center for Computational Neuroscience Freiburg
  • Founding Member of the Center for Applied Biosciences (ZAB), Freiburg, Germany
  • Reviewer for national and international scientific journals, academic institutions and funding agencies
     

Ausgewählte Publikationen

  • Wülfing JM, Kumar SS, Boedecker J, Riedmiller M, Egert U (2019) Adaptive long-term control of biological neural networks with deep reinforcement learning. Neurocomputing 342:66–74, DOI:10.1016/j.neucom.2018.10.084.
  • Okujeni S, Egert U (2019) Self-organization of modular network architecture by activity-dependent neuronal migration and outgrowth. Elife 8:e47966, DOI:10.7554/eLife.47996.
  • Okujeni S, Egert U (2019) Inhomogeneities in network structure and excitability govern initiation and propagation of spontaneous burst activity. Front Neurosci 13:543, DOI:10.3389/fnins.2019.00543.
  • Heining K, Kilias A, Janz P, Häussler U, Kumar A, Haas CA, Egert U (2019) Bursts with high and low load of epileptiform spikes show context-dependent correlations in epileptic mice. eNeuro:10.1523/ENEURO.0299-18.2019, DOI:10.1523/ENEURO.0299-18.2019.
  • Kilias A, Canales A, Froriep UP, Park S, Egert U, Anikeeva P (2018) Optogenetic entrainment of neural oscillations with hybrid fiber probes. J Neural Eng 15:056006, DOI:10.1088/1741-2552/aacdb9.
  • Okujeni S, Kandler S, Egert U. 2017. Mesoscale architecture shapes initiation and richness of spontaneous network activity. J Neurosci 37:3972–3987.
  • Janz P, Schwaderlapp N, Heining K, Häussler U, Korvink JG, von Elverfeldt D, Hennig J, Egert U, LeVan P, Haas CA. 2017. Early tissue damage and microstructural reorganization predict disease severity in experimental epilepsy. Elife 6:e25742.
  • Kumar SS, Wülfing J, Okujeni S, Boedecker J, Riedmiller M, Egert U. 2016. Autonomous optimization of targeted stimulation of neuronal networks. PLOS Comput Biol 12:e1005054.
  • Weihberger O, Okujeni S, Mikkonen JE, Egert U. 2013. Quantitative examination of stimulus-response relations in cortical networks in vitro. J Neurophysiol 109:1764–74.
  • Tetzlaff C, Okujeni S, Egert U, Wörgötter F, Butz M. 2010. Self-organized criticality in developing neuronal networks. PLoS Comput Biol 6:e1001013.