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Prof. Dr. Benedikt Grothe

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Prof. Dr. Benedikt Grothe

Sektionssprecher "Systemische Neurowissenschaften"

Prof. Dr. Benedikt Grothe, Chair of Neurobiology
Program Director, Graduate School of Systemic Neurosciences
Ludwig-Maximilians-Universität München (LMU)
Department Biology II
Großhaderner Str. 2
D – 82152 Planegg-Martinsried
Germany
 
and
 
Max Planck Institute of Neurobiology
Am Klopferspitz 18
D – 82152 Planegg-Martinsried
Germany

Member of the Bavarian Academy of Science (since 2007)
Fellow of the Max Planck Society (since 2014)
Member of the German National Academy of Sciences, Leopoldina (since 2016)
 

Curriculum Vitae

Date of Birth April 08, 1960


Scientific Career

 

2014 – present Fellow of the Max Planck Society
2010 – present Coordinator/Spokesman, DFG Collaborative Research Center 870 “Assembly and Function of Neuronal Circuits”
2009 – 2011 Dean, Faculty of Biology
2006 – present  Director, Graduate School of Systemic Neurosciences (GSNLMU)
2005 – present Founder and Spokesman, Munich Center for Neurosciences (MCNLMU)
2004 – 2007 Acting Director (Chair), Department Biology II, LMU
2003 – present Professor of Neurobiology, Department Biology II, LMU
1999 – 2003 Research Group Leader, Max Planck Institute of Neurobiology, Martinsried
1994 – 1998 Assistent/Oberassistent (equivalent to Ass. Prof.), Zoologisches Institut, LMU
1992 – 1993 Postdoc, New York University, Center for Neural Sciences (Dan. H. Sanes)
1991                     Postdoc, University of Texas at Austin (George D. Pollak)
1990-1991 Curator (tenured), Natural History Museum Munich


Academic  Education

1996                    Habilitation (Zoology), Privatdozent (indep. lecturer) for Zoology, LMU Munich
1988 – 1991 PhD Dissertation (Dr.rer.nat., Faculty of Biology, LMU) Munich
1983 –1988 Dipl. Biol., LMU, Munich


Academic Job Offers and Short Lists

1998 Assist. Prof (Tenure-Track), University of Washington, Department of Biological Structure, Seattle, USA
2000 Secundo loco, Professor (Chair), Animal Physiology, University of Regensburg
2002 Full Professor, Lund University, Biology, Sweden Germany PhD Dissertation
2002 Reader, University College London, Department of Cell and Developmental Biology, U
2002 Secundo loco, Professor (Chair), Université de Fribourg, Medical Center, Switzerland
2003 Professor (Chair), Johan Wolfgang Goethe-Universität Frankfurt a.M., Physiolgie der Medizin, Germany
2007 Director, Parmenides Foundation. Pullach, Germany
2011 Co-Director and Head of Department, Leibniz-Institute for Age Research, Jena, Germany
2015 Full Professor, University of Queensland, Medical Center & Queensland Brain Institute, Australia
2017 Director and Professor, UCL Ear Institute, University College London, UK


Major Research Interests

>100 publications in the area of systemic and auditory neuroscience.
Structure and function of neuronal circuits processing spatio-temporal information, their evolution and development.
Methods in the lab include: comparative electrophysiology in vitro and in vivo, pharmacology, laser- uncaging, optogenetics, comparative anatomyand immunohistochemistry, animal and human psychophysics

 

Selected publications

  • Lingner A, Pecka M, Leibold C, Grothe B (2018) A novel concept for dynamic adjustment of auditory space. Scientific Reports 8:8335
  • Beiderbeck B, Müller N, Myoga MH, Friauf F*, Grothe B*, Pecka M* (2018) Precise inhibition in the auditory brainstem fine‐tunes and facilitates action potential firing. Nature Commun 9:1771
  • Stange-Marten A, Sinclair JL, Fischl MJ, Kopp-Scheinpflug C, Pecka M, Grothe B (2017) Structural and functional adaptations for fast and precise inhibition: constant synaptic delays and accelerated action potential conductance velocity related to sound localization of low frequency sounds. PNAS 114(24): E4851–E4858
  • Ford, MC, Alexandrova O, Cossell L, Stange-Marten A, Sinclair J, Kopp-Scheinpflug C, Pecka M, Attwell D, Grothe B (2015) Tuning of Ranvier node and internode properties in myelinated axons to adjust action potential timing. Nature Communic DOI: 10.1038/ncomms9073
  • Myoga MH, Lehnert S, Leibold C, Felmy F, Grothe B (2014) Precise Timing of Glycinergic Inhibition Controls Coincidence Detection in the Auditory Brainstem. Nature Communic, DOI: 10.1038/ncomms4790
  • Stange A,  Myoga MH,  Lingner A,  Ford MC, Alexandrowa O,  Felmy F, Pecka M, Siveke I, Grothe B (2013) Adaptation in sound localization: from GABAB receptor-mediated synaptic modulation to perception. Nature Neurosci 16:1840-1847
  • Grothe B, Pecka M, McAlpine D (2010) Mechanisms of sound localization in mammals. Physiol Rev 90:983-1012
  • Magnusson AK, Park TJ, Pecka M, Grothe B, Koch U (2008) Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem. Neuron 59:125–137 (equal contributions BG&UK)
  • Grothe B (2003) New roles for synaptic inhibition in sound localization. Nature Rev Neurosci 4: 540-550
  • Brand A, Behrend O, Marquardt T, McAlpine D, Grothe B (2002) Precise inhibition is essential for microsecond interaural time difference coding. Nature 417: 543-547
  • Kapfer C, Seidl AH, Schweizer H, Grothe B (2002) Experience-dependent refinement of inhibitory inputs to auditory coincidence-detector neurons. Nature Neurosci 5: 247-253
  • Grothe B, Vater M, Casseday JH, Covey E (1992) Monaural interaction of excitation and inhibition in the medial superior olive of the mustached bat: an adaptation for biosonar. Proc Nat Acad Sci USA 89: 5108-5112

 


Honours and other pieces of evidence of qualification

  • 1990 Junior research award of the German Zoological Society (DZG)
  • 1992 DFG-Research-Fellowship
  • 2000 Research Award of the German Audiological Society (DGA)
  • 2003 – 2008 Editor Journal of Comparative Physiology A
  • 2005 – present Board Member, Munich Competence Center for Ethics
  • 2007 Heller Lecture (Guest of honour and keynote speaker) Center for Brain Sciences, Hebrew University, Jerusalem)
  • 2007 – elected member of the Bavarian Academy of Science
  • 2007 – 2010 Editor, PLoSONE
  • 2011- 2015 Board of Trustees, Körber-Stiftung (Foundation), Hamburg, Germany
  • 2007 – 2014 Director Member Parmenides Foundation, Munich, Germany
  • 2007 – 2009 LMU strategic council
  • 2008 – 2011 Scientific Advisory Board (Chair), Max Planck Institute of Neurological Research, Cologne,
  • 2009 – 2014 Board of Trustees, Max Planck Institutes of Neurobiology & of Biochemistry, Martinsried
  • 2009 – Editorial Board, Hearing Research
  • 2010 – Order of Merit of the Federal Republic of Germany
  • 2013 – Advisory board „Zukunft der Lehre“, Goethe University Frankfurt a.M., Germany;
  • 2014 – Max Plack Fellow
  • 2015 – Editorial Board Member, Neuroforum
  • 2016 – elected Member of the National Academy of Sciences, Leopoldina

Most important research and teaching collaborations

  • 2004 – present BMBF- Bernstein Center for Computational Neurosciences Munich, BCCN (PI; vice-coordinator 2004 –present )
  • 2006 – present Founder and Speaker of Munich Center for  Neuroscience - Brain and Mind, MCNLMU
  • 2004 – 2014 DFG-GRK 1091 (graduate program) “Orientation and Motion in Space” (PI and vice-coordinator)
  • 2005 – 2015 DFG-GRK 1373 (int. graduate program) “Brain signalling: from neurons to circuits” (PI)
  • 2010 – present Founder and Speaker of DFG-SFB 870 (Collaborative Research Center) “Assembly and Function of Neuronal Circuits in Sensory Processing” (speaker and PI)
  • 2006 – present  Initiator and Head of “M.Sc. Neuroscience”, Master program funded by Elite Network of Bavaria
  • 2006 – preset Founder and Director of Graduate School of Systemic Neurosciences, GNSLMU funded by German Excellence Initiative (2006-2019)
  • 2009 – 2019 “Integrated research and treatment center IFBLMU: Center for vestibular and ocular motor disorders” (PI and board member)
  • 2012 – 2019 PI at ExcellenceCluster “Systems Neurology” SyNergy (PI); spokesman Christian Haass;
  • 2019 – 2025 PI at ExcellenceCluster “Systems Neurology” SyNergy (PI)