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Prof. Dr. Ilona C. Grunwald Kadow

 

Vorstand 2017 - 2019

Prof. Dr. Ilona C. Grunwald Kadow

Sektionssprecherin "Molekulare Neurobiologie"

Technische Universität München
Fakultät der Lebenswissenschaften
Liesel-Beckmann-Str. 4
85354 Freising-Weihenstephan
 
Telefon: +49 (0)8161 71-2801

Email: grunwald@wzw.tum.de
 

Curriculum Vitae

Date of birth    October 16th, 1974
Children 3 children


Academic education

1999-2002 Graduate student, international PhD programme at EMBL and Max Planck Institute of Neurobiology, Laboratory of Prof. R Klein (graduated with Dr. rer. nat. from the University of Heidelberg)
1993-1999    Studies of Biology at the University of Göttingen, Germany and at the University of California, San Diego, U.S.A. (graduated with Master of Biology from the University of Göttingen)


Professional experience

01/2017-                 Professor at the Technical University of Munich, Freising/Weihenstephan
07/2008-12/2016 Max-Planck und Emmy-Noether Group leader at Institute of Neurobiology, Martinsried
2003-2008    Postdoctoral research fellow, University of California, Laboratory of Prof. SL Zipursky, Los Angeles, U.S.A. (from 2006-2008 hosted in the MPI of Neurobiology, Prof. Dr. R Klein)

                   

Awards and Honors

2014 ERC starting grant (start July 2015)
2013 Boehringer Ingelheim Exploration grant
2012 EMBO Young investigator
2010 Member of AcademiaNet – database of excellent female scientists
2008 Career Development award of the Human Frontiers Science Organization
2008 Emmy Noether grant of the German Research Foundation
2003 Otto Hahn Medal of the Max Planck Society

    

Memberships and services to community 
 

  • Speaker of the Max-Planck research groups of the biomedical section (2011-2012)
  • Perspectives committee member of the Biomedical section, Max-Planck Society (2011-2012)
  • Faculty member of the LMU Graduate School of Systemic Neurosciences
  • Associated faculty member of the International Max Planck Research School of Molecular and Cellular Life Sciences
  • Member of the editorial board of ‘Brain and Behavior’
  • Member of AcademiaNet
  • Reviewer for Neuron, PNAS, Current Biology, Nature Communications, Journal of Neuroscience, Neural Development, Molecular Metabolism, Brain and Behavior, Molecular Metabolism, Medical and Veterinary Entomology, PlosONE, Trends in Ecology and Evolution
  • Reviewer for EMBO fellowships, ERC starting grants, Human Frontiers, FWO Belgium, FCT Portugal, MINERVA Foundation, ANR France, Swiss Science Foundation, Marie-Curie fellowships
  • Society of Neurosciences member
  • CIPSM LMU (Ludwig Maximilians University) center of excellence member, Gender equality program (2008-2011)

Scientific Focus

Das Ziel meiner Forschung ist es, sensorische Verarbeitung und Entscheidungsfindungen auf der Ebene neuronaler Vorgänge und Nervennetzwerke im Gehirn zu verstehen. Speziell interessiere ich mich für die Verarbeitung von chemosensorischer Information – Duft und Geschmack.
Der Geruchssinn erlaubt die Diskriminierung einer großen Zahl an Geruchsstoffen. Neurone auf den Geruchsorganen, die spezifische Rezeptoren exprimieren, bilden präzise Verbindungen zu Neuronen in höheren Hirnarealen, die diese Information weiter prozessieren. Die Fähigkeit bestimmte Geruchs- oder Geschmacksstoffe zu identifizieren und zu bewerten ist essentiell für wichtige Verhaltensweisen, wie das Finden und Evaluieren von Nahrung. Wir fragen insbesondere wie Verhaltenskontext, physiologischer Zustand und Erfahrung die sensorische Verarbeitung und Entscheidungen beeinflussen. Mithilfe von inter­disziplinären Ansätzen wie Multiphotonenmikroskopie und Optogenetik untersuchen wir diese Fragestellungen auf drei Ebenen: (i) Verhalten, (ii) neuronale Schaltkreise und (iii) Gene.

Selected Publications

  • Hussain A*, Zhang M*, Üçpunar HK, Svensson T, Quillery E, Gompel N, Ignell R, Grunwald Kadow IC (2016). Ionotropic chemosensory receptors mediate the taste and smell of polyamines. PLoS Biology 14:e1002454. doi:10.1371 * equal contribution
  • Hussain A*, Üçpunar HK*, Zhang M, Loschek LF, Grunwald Kadow IC (2016). Neuropeptides modulate female chemosensory processing upon mating in Drosophila. PLoS Biology 14:e1002455. doi: 10.1371
* equal contribution
  • Lewis L, Siju KP, Aso Y, Friedrich AB, Bulteel AJB, Rubin GM, Grunwald Kadow IC (2015). A higher brain circuit for immediate integration of conflicting sensory information in Drosophila. Current Biology PMID: 26299514, doi: 10.1016/j.cub.2015.07.015
  • Bräcker LB*, Siju KP*, Varela N, Zhang M, Aso Y, Vasconcelos ML, Grunwald Kadow IC (2013). Essential role of the mushroom body in context-dependent CO₂ avoidance in Drososphila. Current Biology 23: 1228-1234. *equal contribution
  • Hartl, M, Loschek, LF, Stephan, D, Siju, KP, Knappmeyer, C, Grunwald Kadow, IC (2011) A New Prospero and microRNA-279 Pathway Restricts CO2 Receptor Neuron Formation. Journal of Neuroscience 31(44): 15660-73.
  • Cayirlioglu, P*, Grunwald Kadow, IC*, Zhan, X, Okamura, K, Gunning, D, Lai, EC, and Zipursky, SL (2008) Hybrid Neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. Science 319, 1256-1260. * equal contribution
  • Jones, WD, Cayirlioglu, P, Grunwald Kadow, IC and Vosshall, LB (2007). Two chemosensory receptors together mediate carbon dioxide detection in Drosophila. Nature 445, 86-90.